New publication: Uterine fluid proteome changes during diapause and resumption of embryo development in roe deer
The first paper of our project on the “Regulation of Embryonic Diapause in the European roe deer” has been published in the journal "Reproduction".
The project aims at elucidating the regulation of developmental pace of embryos. The uterine fluid is the micro-environment in which the diapausing embryo survives for up to 4 to 5 months without negatively affecting its survival. After resumption of development, the embryo rapidly elongates and implants. In this specific study, we analysed the proteins in the uterine fluid. We hypothesised that embryo development during diapause is halted by the lack of signals that support elongation. We found that the diapausing embryo faces an environment with proteins involved in detoxification, and that proteins involved in the cell cycle were higher abundant at elongation than during diapause.
Read the article here: external page Uterine fluid proteome changes during diapause and resumption of embryo development in roe deer
Vera Anna van der Weijden, Jochen Bick, Stefan Bauersachs, Georg J. Arnold, Thomas Fröhlich, Barbara Drews and Susanne E. Ulbrich. Uterine fluid proteome changes during diapause and resumption of embryo development in roe deer. Reproduction, Bristol: BioScientifica, Volume 158: Issue 1, 2019.